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INRA
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Dernière mise à jour : Mai 2018

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Our Publications

  1. Chebib N, Archer F, Bobet-Erny A, Leroux C, Cottin V. 2018. Dysregulation of the endothelin pathway in lymphangioleiomyomatosis with no direct effect on cell proliferation and migration. Sci Rep 8:14698.
  2. Sid, N., N. El Houda Belalmi, L. Benhamza, S. Ouhida, M. Zebiri, A. Aydoğan, and C. Leroux. 2018. First case report of enzootic nasal adenocarcinoma in "Ouled Djellal"ewe in Algeria. Open Veterinary Journal 8:9-12.
  3. Spagnolo, P., and V. Cottin. 2017. Genetics of idiopathic pulmonary fibrosis: from mechanistic pathways to personalised medicine. J Med Genet 54:93-99.
  4. Pain, M., P. J. Royer, J. Loy, A. Girardeau, A. Tissot, P. Lacoste, A. Roux, M. Reynaud-Gaubert, R. Kessler, S. Mussot, C. Dromer, O. Brugiere, J. F. Mornex, R. Guillemain, M. Dahan, C. Knoop, K. Botturi, C. Pison, R. Danger, S. Brouard, A. Magnan, and C. Consortium. 2017. T Cells Promote Bronchial Epithelial Cell Secretion of Matrix Metalloproteinase-9 via a C-C Chemokine Receptor Type 2 Pathway: Implications for Chronic Lung Allograft Dysfunction. Am J Transplant 17:1502-1514.
  5. Maury, J. M., H. Saiedi, and D. Revel. 2017. Pulmonary Artery Embolization after Blunt Trauma. J Vasc Interv Radiol 28:1011.
  6. Maury, J. M., N. Girard, M. Tabutin, R. Grima, L. Chalabreysse, I. Pavlakovic, A. Sayag-Beaujard, C. Leroux, P. J. Souquet, O. Glehen, and F. Tronc. 2017. Intra-Thoracic Chemo-Hyperthermia for pleural recurrence of thymoma. Lung Cancer 108:1-6.
  7. Koutsokera, A., P. J. Royer, J. P. Antonietti, A. Fritz, C. Benden, J. D. Aubert, A. Tissot, K. Botturi, A. Roux, M. L. Reynaud-Gaubert, R. Kessler, C. Dromer, S. Mussot, H. Mal, J. F. Mornex, R. Guillemain, C. Knoop, M. Dahan, P. M. Soccal, J. Claustre, E. Sage, C. Gomez, A. Magnan, C. Pison, L. P. Nicod, and C. C. Sys. 2017. Development of a Multivariate Prediction Model for Early-Onset Bronchiolitis Obliterans Syndrome and Restrictive Allograft Syndrome in Lung Transplantation. Front Med (Lausanne) 4:109.
  8. Greppi, M. C., J. Guillot, E. Melloul, G. Bourdoiseau, O. Lepage, and J. L. Cadore. 2017. Experimental induction of mycotic plaques in the guttural pouches of horses. Medical mycology 55:308-313.
  9. Gomes, M., F. Archer, N. Girard, B. Gineys, C. Dolmazon, A. Bobet Erny, J. F. Mornex, and C. Leroux. 2017. Blocked expression of key genes of the angiogenic pathway in JSRV-induced pulmonary adenocarcinomas. Vet Res 48:76.
  10. Girard, N. 2017. Thymic malignancies: Twisting between autoimmunity and immunotherapy. Lung Cancer 110:68-70.
  11. Demir, S., J. Saison, A. Senechal, and J. F. Mornex. 2017. A severe Mycoplasma pneumoniae pneumonia inducing an acute antibody-mediated pulmonary graft rejection. Lung India 34:85-87.
  12. Cottin, V., E. Bel, P. Bottero, K. Dalhoff, M. Humbert, R. Lazor, R. A. Sinico, P. Sivasothy, M. E. Wechsler, M. Groh, S. Marchand-Adam, C. Khouatra, B. Wallaert, C. Taille, P. Delaval, J. Cadranel, P. Bonniaud, G. Prevot, S. Hirschi, A. Gondouin, B. Dunogue, G. Chatte, C. Briault, C. Pagnoux, D. Jayne, L. Guillevin, J. F. Cordier, and P. Groupe d'Etudes et de Recherche sur les Maladies Orphelines. 2017. Revisiting the systemic vasculitis in eosinophilic granulomatosis with polyangiitis (Churg-Strauss): A study of 157 patients by the Groupe d'Etudes et de Recherche sur les Maladies Orphelines Pulmonaires and the European Respiratory Society Taskforce on eosinophilic granulomatosis with polyangiitis (Churg-Strauss). Autoimmun Rev 16:1-9.
  13. Chebib, N., J. F. Mornex, and V. Cottin. 2017. Subclinical venous access infection and clinical worsening in pulmonary arterial hypertension. J Heart Lung Transplant 36:369-370.
  14. Cadore, J. L., A. Tortereau, S. Belluco, E. Segard, and C. Leroux. 2017. Guttural pouch mycosis in horses: An intriguing and mysterious disease. Equine Vet Educ in press.
  15. Ahmad, K., and V. Cottin. 2017. The challenge of criteria for interstitial pneumonia with autoimmune features. Respir Med 127:67.
  16. Ahmad, K., T. Barba, D. Gamondes, M. Ginoux, C. Khouatra, P. Spagnolo, M. Strek, F. Thivolet-Bejui, J. Traclet, and V. Cottin. 2017. Interstitial pneumonia with autoimmune features: Clinical, radiologic, and histological characteristics and outcome in a series of 57 patients. Respir Med 123:56-62.
  17. Leroux, C., and R. F. Cook. 2016. Equine infectious anaemia virus, p. 177-189. In D. Liu (ed.), Molecular Detection of Animal Viral Pathogens. CRC Press.
  18. Chebib, N., C. Khouatra, R. Lazor, F. Archer, C. Leroux, D. Gamondes, F. Thivolet-Bejui, J. F. Cordier, and V. Cottin. 2016. [Pulmonary lymphangioleiomyomatosis: From pathogenesis to management]. Rev Mal Respir 33:718-734.
  19. Bonnefont-Rebeix, C., C. Fournel-Fleury, F. Ponce, S. Belluco, D. Watrelot, S. E. Bouteille, S. Rapiteau, D. Razanajaona-Doll, J. J. Pin, C. Leroux, and T. Marchal. 2016. Characterization of a novel canine T-cell line established from a spontaneously occurring aggressive T-cell lymphoma with large granular cell morphology. Immunobiology 221:12-22.
  20. Bolfa, P., F. Barbuceanu, S. E. Leau, and C. Leroux. 2016. Equine infectious anaemia in Europe: Time to re-examine the efficacy of monitoring and control protocols? Equine Vet J 48:140-142.
  21. Monot, M., A. Erny, B. Gineys, S. Desloire, C. Dolmazon, A. Aublin-Gex, V. Lotteau, F. Archer, and C. Leroux. 2015. Early Steps of Jaagsiekte Sheep Retrovirus-Mediated Cell Transformation Involve the Interaction between Env and the RALBP1 Cellular Protein. J Virol 89:8462-8473.
  22. Monot, M., F. Archer, M. Gomes, J. F. Mornex, and C. Leroux. 2015. Advances in the study of transmissible respiratory tumours in small ruminants. Vet Microbiol 181:170-177.
  23. Cook, R. F., C. Leroux, and C. J. Issel. 2013. Equine infectious anemia and equine infectious anemia virus in 2013: a review. Vet Microbiol 167:181-204.
  24. Bolfa, P., M. Nolf, J. L. Cadore, C. Catoi, F. Archer, C. Dolmazon, J. F. Mornex, and C. Leroux. 2013. Interstitial lung disease associated with Equine Infectious Anemia Virus infection in horses. Vet Res 44:113.
  25. Archer, F., A. Abi-Rizk, S. Desloire, C. Dolmazon, B. Gineys, F. Guiguen, V. Cottin, J. F. Mornex, and C. Leroux. 2013. Lung progenitors from lambs can differentiate into specialized alveolar or bronchiolar epithelial cells. BMC Vet Res 9:224.
  26. Viginier, B., C. Dolmazon, I. Lantier, F. Lantier, F. Archer, C. Leroux, and C. Terzian. 2012. Copy Number Variation and Differential Expression of a Protective Endogenous Retrovirus in Sheep. PLos ONE 7:e41965.
  27. Lutringer-Magnin, D., N. Girard, J. Cadranel, C. Leroux, E. Quoix, V. Cottin, C. D. Signore, M. P. Lebitasy, G. Cordier, P. Vanhems, and J. F. Mornex. 2012. Professional Exposure to Goats Increases the Risk of Pneumonic-Type Lung Adenocarcinoma: Results of the IFCT-0504-Epidemio Study. PLos ONE 7:e37889.
  28. Bolfa, P. F., C. Leroux, A. Pintea, S. Andrei, C. Catoi, M. Taulescu, F. Tabaran, and M. Spinu. 2012. Oxidant-antioxidant imbalance in horses infected with equine infectious anaemia virus. Vet J 192:449-454.
  29. Archer, F., J. F. Mornex, and C. Leroux. 2012. Interplay between JSRV, an oncogenic retrovirus, and the pulmonary epithelium. Current Immunology Reviews 7:209-215.
  30. Cottin, V., F. Archer, C. Leroux, J. F. Mornex, and J. F. Cordier. 2011. Milestones in lymphangioleiomyomatosis research. Eur Respir Rev 20:3-6.
  31. Leroux, C., J. C. Cruz, and J. F. Mornex. 2010. SRLVs: a genetic continuum of lentiviral species in sheep and goats with cumulative evidence of cross species transmission. Curr HIV Res 8:94-100.
  32. Leroux, C., and J. F. Mornex. 2008. Retroviral infections in sheep and the associated diseases. Small Rumin Res 76:68-76.
  33. Kaufmann, C., M. Brechbuhl, A. Oevermann, S. Muller, K. Zimmer, M. Schonmann, C. Leroux, D. Weibel, and G. Bertoni. 2008. [Enzootic nasal adenocarcinoma in a dairy sheep flock]. Schweiz Arch Tierheilkd 150:297-302.
  34. Erhouma, E., F. Guiguen, Y. Chebloune, D. Gauthier, L. M. Lakhal, T. Greenland, J. F. Mornex, C. Leroux, and T. Alogninouwa. 2008. Small ruminant lentivirus proviral sequences from wild ibexes in contact with domestic goats. J Gen Virol 89:1478-1484.
  35. Varela, M., M. Golder, F. Archer, M. de Las Heras, C. Leroux, and M. Palmarini. 2007. A large animal model to evaluate the effects of Hsp90 inhibitors for the treatment of lung adenocarcinoma. Virology 371:206-215. 
  36. Leroux, C., N. Girard, V. Cottin, T. Greenland, J. F. Mornex, and F. Archer. 2007. Jaagsiekte Sheep Retrovirus (JSRV): from virus to lung cancer in sheep. Vet Res 38:211-228.
  37. Bonnefont-Rebeix, C., T. Marchal, J. Bernaud, J. J. Pin, C. Leroux, S. Lebecque, L. Chabanne, and D. Rigal. 2007. Toll-like receptor 3 (TLR3): A new marker of canine monocytes-derived dendritic cells (cMo-DC). Vet Immunol Immunopathol 118:134-139.
  38. Boissin-Quillon, A., D. Piau, and C. Leroux. 2007. In silico segmentations of lentivirus envelope sequences. BMC Bioinformatics 8:99.
  39. Archer, F., E. Jacquier, M. Lyon, J. Chastang, V. Cottin, J. F. Mornex, and C. Leroux. 2007. Alveolar type II cells isolated from pulmonary adenocarcinoma: a model for JSRV expression in vitro. Am J Respir Cell Mol Biol 36:534-540.
  40. Suau, F., N. Girard, F. Archer, V. Cottin, S. Croze, J. F. Mornex, and C. Leroux. 2006. JSRV (jaagsiekte sheep retrovirus) et cancer du poumon associé chez le mouton. Virologie 10:287-299.
  41. Suau, F., V. Cottin, F. Archer, S. Croze, J. Chastang, G. Cordier, F. Thivolet-Bejui, J. F. Mornex, and C. Leroux. 2006. Telomerase activation in a model of lung adenocarcinoma. Eur Respir J 27:1175-1182.
  42. Leroux, C., R. C. Montelaro, E. Sublime, and J. L. Cadore. 2005. EIAV (equine infectious anemia virus): mieux comprendre la pathogénèse des infections lentivirales. Virologie 9:289-300.
  43. Salaun, B., B. de Saint-Vis, N. Pacheco, Y. Pacheco, A. Riesler, S. Isaac, C. Leroux, V. Clair-Moninot, J. J. Pin, J. Griffith, I. Treilleux, S. Goddard, J. Davoust, M. Kleijmeer, and S. Lebecque. 2004. CD208/dendritic cell-lysosomal associated membrane protein is a marker of normal and transformed type II pneumocytes. Am J Pathol 164:861-871.
  44. Leroux, C., J. L. Cadore, and R. C. Montelaro. 2004. Equine Infectious Anemia Virus (EIAV): what has HIV's country cousin got to tell us? Vet Res 35:485-512.
  45. Chalabreysse, L., C. Leroux, J. F. Obadia, T. Greenland, F. Thivolet-Bejui, and J. F. Mornex. 2004. Apoptosis in right-ventricle biopsy is not predictive of graft survival. Transpl Int 17:362-365.
  46. Mornex, J. F., F. Thivolet, M. De las Heras, and C. Leroux. 2003. Pathology of human bronchioloalveolar carcinoma and its relationship to the ovine disease. Curr Top Microbiol Immunol 275:225-248.
  47. DeMartini, J. C., J. O. Carlson, C. Leroux, T. Spencer, and M. Palmarini. 2003. Endogenous retroviruses related to jaagsiekte sheep retrovirus. Curr Top Microbiol Immunol 275:117-137.
  48. Carlson, J., M. Lyon, J. Bishop, A. Vaiman, E. Cribiu, J. F. Mornex, S. Brown, D. Knudson, J. DeMartini, and C. Leroux. 2003. Chromosomal distribution of endogenous Jaagsiekte sheep retrovirus proviral sequences in the sheep genome. J Virol 77:9662-9668.
Dysregulation of the endothelin pathway in lymphangioleiomyomatosis

Dysregulation of the endothelin pathway in lymphangioleiomyomatosis with no direct effect on cell proliferation and migration

Published in Sci Rep. 2018 Oct 2;8(1):14698. doi: 10.1038/s41598-018-32795-3
Read more
Blocked expression of key genes of the angiogenic pathway in JSRV-induced pulmonary adenocarcinomas

Blocked expression of key genes of the angiogenic pathway in JSRV-induced pulmonary adenocarcinomas

Vet Res. 2017 Nov 14;48(1):76. doi: 10.1186/s13567-017-0480-z
Read more
First case report of enzootic nasal adenocarcinoma in

First case report of enzootic nasal adenocarcinoma in "Ouled Djellal" ewe in Algeria

Published in Open Vet J. 2018;8(1):9-12. doi: 10.4314/ovj.v8i1.3. Epub 2018 Jan 19
Read more
RALBP1

Early Steps of Jaagsiekte Sheep Retrovirus-Mediated Cell Transformation Involve the Interaction between Env and the RALBP1 Cellular Protein

Published in J Virol. 2015 Aug;89(16):8462-73. doi: 10.1128/JVI.00590-15. Epub 2015 Jun 3
Read more